Toxoplasma gondii and multiple sclerosis: a population-based case-control study.

At univariate analysis MS was strongly associated with education with a significant trend (chi square 23.5; p-value 0.0003) reaching a strongest positive association for university degree (OR 6.87; 95%CI 2.90–16.20; p-value < 0.0001); MS was also positively associated with history of mononucleosis and inversely associated with history of autoimmune diseases as reported in Table 2 .

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We found a negative association, even if borderline significant, between T. gondii seropositivity and presence of autoimmune diseases (0.54; 95%CI 0.25–1.16; p-value 0.1).

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