In addition, 117 non-NME FDC drugs (new combinations containing only already-marketed drugs) were approved, with a clear trend for increasing numbers of approval: on average 1.2 approvals per year in the 1980s to 5.9 per year in the 2000s and 7.0 per year in the period 2010–2012.
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Trends in licence approvals for ophthalmic medicines in the United Kingdom.
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