Barely Significant
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Prevention of infection in primary THA and TKA.

EFORT Open Rev · 2020 · PMC7608519 · PMID 33204502

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We established an infection rate of 0.8% in the control group and 0.7% in the intervention group, although our findings did not reach statistical significance. 90 More recently, we performed a meta-analysis incorporating 25 RCTs and 11,957 patients showed that triclosan-coated sutures significantly reduced the rate of SSI at 30 days (RR 0.73, 95% CI 0.65–0.82). 91 Ten RCTs within this meta-analysis were focused on clean surgery, for which a significantly lower incidence of SSI (149/3029) occurred with triclosan-coated sutures compared to standard sutures (230/1117) (RR 0.71, 95% CI 0.58–0.88).

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