Barely Significant
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Pathway-specific dysregulation of striatal excitatory synapses by LRRK2 mutations.

Elife · 2020 · PMC7609054 · PMID 33006315

Europe PMCDOI
1
hedged sentence
0.0904
closest p · 1.8× alpha
0.0904
boldest claim

The sentences

showed a trendp=0.0904so close (0.05 < p ≤ 0.1)
Given that the PSD95 area in +/GS dSPNs showed a trend towards decrease (+/RC, 94% of control, +/GS , 83% of control, one-way ANOVA p=0.0904, post-hoc +/+ vs +/GS p=0.075) ( Figure 2—figure supplement 1A,B ), we evaluated the percentage of the GluA1-PSD95 overlap relative to the total PSD95 area across genotypes. 32% of total PSD95 area contained GluA1 in +/RC dSPNs, compared to 23% in +/+ neurons, and 26% in +/GS neurons (one-way ANOVA p=0.0015, post hoc tests as noted) ( Figure 2H ).

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