Water contact angle is not a good predictor of biological responses to materials.

Biointerphases · 2017 · PMC7613460 · PMID 28683556

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a clear trendno p-value reported

Furthermore, when diverse rather 27 , 28 then chemically similar libraries of materials 19 , 21 are studied, it is clear that there is rarely a clear trend in the cell number versus water contact angle data.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.