Long-term retention of antigens in germinal centers is controlled by the spatial organization of the follicular dendritic cell network.

Even though we couldn’t detect differences in BCR affinity in the Cr2 -HET mice ( Figure 7B ), there was a trend of reduced antigen-specific PB and PC differentiation contrasting with intact memory B cell differentiation ( Figure 7E, F ), although this did not reach statistical significance.

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