However, Chil1 mRNA expression was less in C57BL/6 compared with BALB/c mice, although this did not reach statistical significance in this data set ( P = 0.07 for DRA C57BL/6 versus DRA BALB/c mice at week 4 or 8).
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The magnitude of airway remodeling is not altered by distinct allergic inflammatory responses in BALB/c versus C57BL/6 mice but matrix composition differs.
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