Sites of active gene regulation in the prenatal frontal cortex and their role in neuropsychiatric disorders.

Moreover, SNP heritability for schizophrenia, bipolar disorder, and major depressive disorder was enriched at Bonferroni-corrected significance in NeuN+ OCRs overlapping either fetal H3K4me1 sites ( Figure 5 ) or H3K4me3 sites, with nominally significant enrichments observed for ASD in NeuN+ OCRs overlapping H3K4me1 sites and for ADHD in NeuN+ OCRs overlapping H3K4me3 sites ( Table S3 ).

also in 7,732 other papers