An analysis on the role of glucagon-like peptide 1 receptor agonists in cognitive and mental health disorders.

Overall, we identified 280 pre-clinical/mechanistic ( Figure 1 and Supplementary Information S4 and S5 ) and 96 clinical studies ( Tables 1 - 6 , Figure 2 , Extended Data Figure 1 , Extended Data Tables 1 - 6 , and Supplementary Information S2 ), with a clear trend of growing relevant literature over the past few years as the use of these medications becomes more widespread and their indications expand far beyond the initial intentions of the manufacturers 222 .

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