Evolution from adherent to suspension: systems biology of HEK293 cell line development.

Sci Rep · 2020 · PMC7642379 · PMID 33149219

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showed a trendno p-value reported

A comparison between gene expression fold changes and copy number variation of the differentially expressed genes (log2-fold change > ± 1) for each progeny cell line compared to HEK293 showed a trend of gained gene copies amongst the majority of genes with up-regulated mRNA levels (Supplementary Fig.

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