-specific mortality compared with high/moderate tumor grade (HR = 1.211, 95% CI = 1.184–1.239 for poor/anaplastic tumor grade; HR = 1.087, 95% CI = 1.027–1.152 for unknown tumor grade; using high/moderate tumor grade as the reference, P < 0.0001), whereas the difference between different histotypes did not reach statistical significance (HR = 1.012, 95% CI = 0.980–1.045; using adenocarcinoma histology, P = 0.482); receiving chemotherapy was independently associated with 35.6% decreased risk of cancer-specific mortality compared with not receiving chemotherapy (HR = 0.644, 95% CI = 0.629–0.660; using no chemotherapy as the reference, P < 0.0001).
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Oncologic Outcome and Efficacy of Chemotherapy in Colorectal Cancer Patients Aged 80 Years or Older.
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