Clustering of Alzheimer's and Parkinson's disease based on genetic burden of shared molecular mechanisms.

They were not identical to the ones identified in each disease individually, but showed a highly significant overlap in both cases ( p < 1E−16, χ 2 -test).

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According to our analysis, no statistically significant differences of cognitive assessment scores could be found between clusters in AD patients at study baseline (although we notably did observe weakly significant results for working memory cognition assessments in ROSMAP patients).

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