A preliminary exploration of acute intracranial pressure-cerebrospinal fluid production relationships in experimental hydrocephalus.

However, there was a strong trend in the hydrocephalic group when rats were at 90° ( P = 0.0004), indicating that in hydrocephalic animals, the mean ICP decreased as weight increased.

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The degree of ventriculomegaly, as grouped into the saline control (Evan's Index of < 0.30) and kaolin (Evan's Index ≥0.46) groups, does not significantly affect baseline ICP or flow, although there was an obvious trend in both the area under the curve and mean values showing that dependence exists between ICP and postural change in nonhydrocephalic animals that is ablated in hydrocephalic animals ( P = 0.1973).

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