X-Linked Hypophosphatemia: A New Era in Management.

J Endocr Soc · 2020 · PMC7649833 · PMID 33204932

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did not reach statistical significanceno p-value reported

Bone pain and physical function appeared to improve with burosumab compared with placebo but the reductions did not reach statistical significance.

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a nonsignificant trendno p-value reported

Some studies have found a nonsignificant trend toward more serious manifestations in males compared with females, potentially due to X-inactivation [ 9 , 17-19 ].

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