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Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure.

Eur Respir J · 2021 · PMC7651836 · PMID 33154030

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Exposure of human lung tissue to severe COVID-19 plasma caused loss of the junctional molecule occludin while changes in VE-cadherin protein levels did not reach statistical significance ( figure 1d ).

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