Developing and validating an integrated gross tumor volume (GTV)-TNM stratification system for supplementing unresectable locally advanced non-small cell lung cancer treated with concurrent chemoradiotherapy.

1 a), ECOG score (3-year OS, ECOG 0 vs 1 vs 2, 68.2% vs 63.1% vs 33.1%, P = 0.001), weight loss ≥ 5 kg (3-year OS, yes vs no, 38.7% vs 62.2%, P = 0.018) and age (3-year OS, < 58 years vs ≥ 58 years, 66.8% vs 54.4%, P = 0.088) were significantly associated with OS, while TNM stage failed to reach statistical significance (3-year OS, stage IIIA vs IIIB vs IIIC, 58.7% vs 65.3% vs 49.7%, P = 0.127) (Fig. 1 b).

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