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Mycophenolic acid, the active form of mycophenolate mofetil, interferes with IRF7 nuclear translocation and type I IFN production by plasmacytoid dendritic cells.

Arthritis Res Ther · 2020 · PMC7654586 · PMID 33168076

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Although the transcriptional upregulation of IRF-7 trended to lower following treatment with MPA, this difference did not reach statistical significance.

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