The mRNA and protein expression of MMP13, LC3, and Beclin1 showed a trend that was similar to the immunohistochemistry results ( Figure 14E and 14F ).
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Down-regulated ciRS-7/up-regulated miR-7 axis aggravated cartilage degradation and autophagy defection by PI3K/AKT/mTOR activation mediated by IL-17A in osteoarthritis.
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