IL-6 Inhibition in Critically Ill COVID-19 Patients Is Associated With Increased Secondary Infections.

Front Med (Lausanne) · 2020 · PMC7655919 · PMID 33195334

Europe PMC DOI

hedged sentences

0.0740

closest p · 1.5× alpha

0.1120

boldest claim

The sentences

did not reach statistical significancep = 0.074so close (0.05 < p ≤ 0.1)

While steroid administration did not reach statistical significance, there was a trend toward steroids being positively associated with bacterial infections [OR, 2.76 (95% CI, 0.91–9.02); p = 0.074].

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a trend toward significancep = 0.112not close (p > 0.1)

Additionally, there were three patients with fungal infections with one patient having the fungal infection in two different locations in the tocilizumab group compared with none in the non-tocilizumab group with statistical analysis showing a trend toward significance ( p = 0.112).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.