Barely Significant
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A Persisting Nontropical Focus of Burkholderia pseudomallei with Limited Genome Evolution over Five Decades.

mSystems · 2020 · PMC7657595 · PMID 33172968

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a clear trendno p-value reported
We did not observe a clear trend in our 51-year B. pseudomallei data set, finding limited evidence of a correlation between mutation patterns and time.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.