Correlations of Calf Muscle Macrophage Content With Muscle Properties and Walking Performance in Peripheral Artery Disease.

Quantification of the total number of CD11b+ macrophages showed that the average number of macrophages/fiber was higher in muscles from participants with PAD compared with participants without PAD, but the difference did not reach statistical significance after adjusting for race (0.63/fiber versus 0.44/fiber, P =0.139) (Figure 2 A), likely attributable to the highly variable number of total macrophages in muscles from participants with PAD compared with patients without PAD (0.07–1.57/fiber versus 0.23–0.66/fiber, respectively).

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