Although rats in the free hMSC group showed a trend toward less pain in time, a significant difference compared with the saline-treated group was only reached at the end of the experiment at week 8 (saline control vs. free hMSC, p = 0.036).
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MSC encapsulation in alginate microcapsules prolongs survival after intra-articular injection, a longitudinal in vivo cell and bead integrity tracking study.
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