Cooperative participation of epigenomic and genomic alterations in the clinicopathological diversity of gastric adenocarcinomas: significance of cell adhesion and epithelial-mesenchymal transition-related signaling pathways.

Representative maps of the pathways that showed modest significance and were included in Table 1 and Supplementary Table S11 , available at Carcinogenesis Online, such as ‘E-cadherin signaling and its regulation in gastric cancer (FDR = 0.004 and P < 0.001 for Cluster B1)’ and ‘Development_Regulation of EMT (FDR = 0.002 and P < 0.001 for Cluster B1)’, are illustrated schematically in Figure 4 using MetaCore software.

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