Are neuropsychiatric symptoms in dementia linked to CSF biomarkers of synaptic and axonal degeneration?

Alzheimers Res Ther · 2020 · PMC7670701 · PMID 33203439

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

showed a trendp = 0.06so close (0.05 < p ≤ 0.1)

However, AD patients younger than 70 years of age with high NPS burden showed a trend towards significantly ( p = 0.06) decreased levels of Ng as compared to “low NPS” AD patients.

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almost significantlyp = 0.06so close (0.05 < p ≤ 0.1)

Results No significant differences were seen in the CSF levels of Ng, GAP-43, and NFL between AD patients with high vs low levels of NPS (but almost significantly decreased for Ng in AD patients < 70 years with high NPS, p = 0.06).

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