MeCP2 gates spatial learning-induced alternative splicing events in the mouse hippocampus.

We found that in control animals that underwent learning, GO terms associated with “Dendritic spine” and “Positive regulation of spine development” were predominantly enriched in the inclusion group (−log 10 P value < 3), whereas terms associated with “Alternative splicing” and “Splice variant” showed a trend for enrichment in the exclusion cohort (−log 10 P value < 3) [see Additional file 6 : Table S4].

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