The DARC-null trait is associated with moderate modulation of NK cell profiles and unaltered cytolytic T cell profiles in black South Africans.

PLoS One · 2020 · PMC7676658 · PMID 33211774

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a weak trendp = 0.08so close (0.05 < p ≤ 0.1)

Although NK cell subset frequencies were not significantly different when stratified by DARC genotype irrespective of HIV status ( Fig 2C and 2D ), a weak trend was noted towards higher frequencies of immature CD56 bright cells in DARC-null compared to DARC-positive HIV negative donors (p = 0.08, Fig 2C ).

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showed a trendp = 0.09so close (0.05 < p ≤ 0.1)

In addition, NK cells from HIV-infected persons also showed a trend of higher expression of exhaustion marker PD-1 compared to uninfected individuals (p = 0.09, Fig 3F ).

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