Grape Seed Extract Polyphenols Improve Resistance Artery Function in Pregnant eNOS^-/- Mice.

In a recently published work ( Finn-Sell et al., 2018 ), maternal supplementation with pomegranate juice had detrimental effects on fetal outcomes of both WT and eNOS –/– mice; whereas, treatment with resveratrol showed a trend toward an increase in fetal weight in eNOS –/– mice ( Poudel et al., 2013 ) and the antioxidant drug Tempol (4-Hydroxy-2,2,6,6-tetramethylpiperidin-1-oxyl) improved fetal growth in eNOS –/– mice ( Stanley et al., 2012 ).

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