GPR183 Regulates Interferons, Autophagy, and Bacterial Growth During <i>Mycobacterium tuberculosis</i> Infection and Is Associated With TB Disease Severity.

GPR183 knockdown ( Supplementary Figure 4C ) up-regulated IFNB1 (2.7–5.5 fold; P = 0.0115) as well as IRF1, IRF3, IRF5 , and IRF7 , although the latter did not reach statistical significance ( Figure 3A ).

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