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Desipramine, commonly used as a noradrenergic neuroprotectant in 6-OHDA-lesions, leads to local functional changes in the urinary bladder and gastrointestinal tract in healthy rats.

Heliyon · 2020 · PMC7679251 · PMID 33251357

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showed a trendno p-value reported
injections of desipramine, showed a trend of less contractility, as seen in high K + response per mg tissue, which coincides with a significantly reduced response following both EFS and methacholine stimulations.

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