Quality of life for older patients with cancer: a review of the evidence supporting melatonin use.

Only one double-blind trial [ 67 ], recently studied the effect of melatonin supplementation (10 or 20 mg/day) on QoL and reported a better meanadjusted QoL score (FACT-L) with a slightly significant better score (2.69 points, CI 0.01–5.38, p = 0.049) found for social wellbeing.

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