Histone modifications associated with gene expression and genome accessibility are dynamically enriched at Plasmodium falciparum regulatory sequences.

Two of the schizont-stage putative promoters had greater promoter activity than the AT content-matched control sequence (ANOVA p = 0.0205, Sidak’s multiple comparisons test PF3D7_1362000 p = 0.0196, PF3D7_0920700 p = 0.0228) and the trend to greater activity approached significance for the third schizont-stage putative promoter (PF3D7_1460600 p = 0.0908), but none of the three ring-stage putative promoters had greater activity than the AT content-matched control sequence (Fig. 10 ).

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