Role of biomarkers in evaluation, treatment and clinical studies of pulmonary arterial hypertension.

Pulm Circ · 2020 · PMC7682212 · PMID 33282185

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nominally significantno p-value reported

An RNA LASSO model consisting of 25 genes was found to predict survival in PAH; 372 of the 507 top dysregulated genes from the whole blood RNAseq study were present in the lung tissue microarray study 44 and 161/372 (43%) were also directionally consistent; 41/161 (25%) genes were nominally significant and 26 met false discovery rate (FDR) corrected significance.

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