showed a trendp = 0.094264
A dichotomized analysis of poor outcome (mRS ≥ 4) and favourable outcome (mRS ≤ 3) showed a trend of higher day 1 S1P levels in patients with poor outcome without reaching statistical significance (Wilcoxon Mann Whitney test, Z = 1.673, p = 0.094264) (Fig. 2 b).