Tcf4 haploinsufficient mice showed a strong trend towards lower densities of radial glia-like stem/precursor cells [NESTIN + cells/μm 3 : control 1.82 × 10 –5 ± 1.94 × 10 –6 ; Tcf4 Het 1.31 × 10 –5 ± 1.35 × 10 –6 ; p-value = 0.0570 (Fig. 2 c)].
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Enriched environment ameliorates adult hippocampal neurogenesis deficits in Tcf4 haploinsufficient mice.
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