Systematic identification of <i>cis</i>-regulatory variants that cause gene expression differences in a yeast cross.

Further, there were significant correlations between the number of nominally significant (p<0.05) MPRA variants identified for a gene and that gene’s local eQTL LOD score (rho = 0.12, p=0.003) and its absolute eQTL effect size (rho = 0.14, p=3e-5).

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This variant was highly significant in the MPRA ( Figure 2B ), while a second variant in the OLE1 promoter was not ( Figure 2A ).

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