The palmitoyl acyltransferase ZDHHC14 controls Kv1-family potassium channel clustering at the axon initial segment.

The sample size (N) varies quite dramatically sometimes within the same graph and analysis – it is unclear how sometimes highly significant results are obtained from comparisons of N=3-13 within the same test. 2) The authors chose to treat individual neurons (Figure 3 and supplements, Figure 4, Figure 7) as biological replicates.

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We note that the total amount of AIS-localized Kv1.2 was significantly reduced, even though the reduction in Kv1.2 mean intensity at the AIS did not reach statistical significance ( Figure 7G,H ).

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