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Toll-Like Receptor Agonists as Adjuvants for Allergen Immunotherapy.

Front Immunol · 2020 · PMC7688745 · PMID 33281825

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In a small phase I/IIa RDBPCT, a sublingual combination of allergen and MPL showed a trend for a reduction in the proportion of positive nasal challenge tests and reduced IgE and enhanced IgG compared to grass pollen sublingual immunotherapy alone ( 94 ).

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