Barely Significant
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Downregulation of Sirt1 is correlated to upregulation of p53 and increased apoptosis in epicardial adipose tissue of patients with coronary artery disease.

EXCLI J · 2020 · PMC7689241 · PMID 33250679

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an increasing trendno p-value reported
The expression of Bcl-2 gene did not differ between groups and an increasing trend was observed for Bax/Bcl-2 ratio in CAD patients; however, it did not reach statistical significance (Figure 3 (Fig. 3) ).

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