The expression of Bcl-2 gene did not differ between groups and an increasing trend was observed for Bax/Bcl-2 ratio in CAD patients; however, it did not reach statistical significance (Figure 3 (Fig. 3) ).
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Downregulation of Sirt1 is correlated to upregulation of p53 and increased apoptosis in epicardial adipose tissue of patients with coronary artery disease.
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