Preclinical platform for long-term evaluation of immuno-oncology drugs using hCD34+ humanized mouse model.

However, in terms of long-term survival, the 45-week survival rate was higher in the busulfan group (64.3%, 9/14 humanized mice) than in the irradiation group (20%, 4/20 humanized mice) and Kaplan-Meier survival analysis also showed a trend toward longer survival in busulfan group than radiation group ( figure 2B ; p =0.071).

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