Human P2X7 Receptor Causes Cycle Arrest in RPMI-8226 Myeloma Cells to Alter the Interaction with Osteoblasts and Osteoclasts.

Cells · 2020 · PMC7690412 · PMID 33105696

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did not reach statistical significanceno p-value reported

Presence of both osteoblasts and osteoclasts (HMCL + OB + OC) reduced RPMI-8226 viability (13.33% with 300 μM BzATP versus 25% with 0 μM BzATP) and was prevented by P2X7 receptor antagonist (25% with 1 μM AZ11645373), but these findings did not reach statistical significance ( Table 2 ).

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