Investigating microstructure of white matter tracts as candidate endophenotypes of Social Anxiety Disorder - Findings from the Leiden Family Lab study on Social Anxiety Disorder (LFLSAD).

Neuroimage Clin · 2020 · PMC7691726 · PMID 33395984

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

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The sentences

near-significantp = 0.06so close (0.05 < p ≤ 0.1)

In accordance with findings from the voxelwise TOI analyses, mean FA in the left SLF demonstrated a significant positive association with levels of self-reported social anxiety (β = 0.002, p = 0.03) and a near-significant association with levels of FNE (β = 3.67E-04, p = 0.06).

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marginally significantp = 0.09so close (0.05 < p ≤ 0.1)

This finding was coupled with a significant negative association with mean RD values (β = −4.39E-07, p = 0.04) and a marginally significant, negative association with mean MD values (β = −3.15E-07, p = 0.09). 3.3 Heritability Per TOI, heritability of every WM parameter was estimated over its average value.

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