Hyperphosphatemia Drives Procoagulant Microvesicle Generation in the Rat Partial Nephrectomy Model of CKD.

However, unlike our earlier in vitro study in cultured endothelial cells [ 9 ], in which 2.5 mM Pi triggered release of endothelial MVs in the microparticle size range of 100–1000 nm diameter, here, an apparent increase was seen in this range but failed to reach statistical significance ( Figure 2 b).

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