Highly significant decrease for saturated intermediate-length acyl chains as 18:0 SM, 20:0 SM, and 22:0 SM was found in 1α,25(OH) 2 D 3 treated U251 and LN18 cells in comparison with untreated cells ( Figure 4 d).
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Effect of 1α,25(OH)<sub>2</sub> Vitamin D<sub>3</sub> in Mutant P53 Glioblastoma Cells: Involvement of Neutral Sphingomyelinase1.
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The data showed a trend of not change of VDR with 100 nM 1α,25(OH) 2 VD3 and a slight downregulation with 100 nM 1α,25(OH) 2 VD3 ( Figure 2 ).