The PAR2 inhibitor I-287 selectively targets Gα<sub>q</sub> and Gα<sub>12/13</sub> signaling and has anti-inflammatory effects.

Commun Biol · 2020 · PMC7695697 · PMID 33247181

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did not reach statistical significanceno p-value reported

Although a similar tendency was observed for the hTrypsin promoted response, the inhibition did not reach statistical significance.

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