Bioinformatics identification and pharmacological validation of Kcnn3/K_Ca2 channels as a mediator of negative affective behaviors and excessive alcohol drinking in mice.

There were significant main effects for treatment ( F 2,64 = 6.78; p = 0.0021) and drug ( F 1,64 = 12.18; p = 0.0009), but the interaction did not reach statistical significance ( F 2,64 = 2.67; p = 0.0772; n = 11–12 mice/group; Fig. 3C ).

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