Mutation-independent Proteomic Signatures of Pathological Progression in Murine Models of Duchenne Muscular Dystrophy.

The expression of the corresponding mRNA transcripts was determined in parallel, which mirrored the protein expression data in the case of Mvp and Pak1 , consistent with their transcriptional upregulation in dystrophic muscle, although some changes between WT and the dystrophic groups did not reach statistical significance at the P < 0.05 level ( Fig. 7 C ).

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