The cumulative scores obtained with CIBERSORT and MCP-counter showed a trend of colinearity with IIS, TIS, and CYT: all algorithms indicated that K/P WT tumors were colder in general compared with K/P -mutated GISTs as they were miniGISTs compared with overt GISTs ( Figure 5A ).
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Tumor genotype, location, and malignant potential shape the immunogenicity of primary untreated gastrointestinal stromal tumors.
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