Barely Significant
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NLRP3 inflammasome deficiency attenuates metabolic disturbances involving alterations in the gut microbial profile in mice exposed to high fat diet.

Sci Rep · 2020 · PMC7712828 · PMID 33273482

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showed a trendno p-value reported
WT mice fed a HFD showed a trend towards increased expression of NLRP3, but this difference was not statistical significant ( P = 0.06).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.