<i>NPM1</i>-Mutated Myeloid Neoplasms with <20% Blasts: A Really Distinct Clinico-Pathologic Entity?

In the series by Peng et al., a comparison with 144 CMML patients without NPM1 mutations documented that NPM1 -mutated cases presented more severe anemia, higher BM monocyte percentage, an increased tendency to AML progression and shorter OS, although these two latter comparisons did not reach statistical significance [ 71 ].

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