Optimizing PSMA Radioligand Therapy for Patients with Metastatic Castration-Resistant Prostate Cancer. A Systematic Review and Meta-Analysis.

Int J Mol Sci · 2020 · PMC7730994 · PMID 33260535

Europe PMC DOI

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a clear trendno p-value reported

Surprisingly, publications on 255 Act PRLT in our systematic review did not show a clear trend in favor of 225 Act PRLT compared with 177 Lu PRLT as second-line treatment after failure to the first series of PRLT.

also in 19,460 other papers

highly significantno p-value reported

The findings were reproducible, marked, and highly significant. 177 Lu PRLT gave a low rate of severe adverse effects irrespective of the studies of 177 Lu PRLT used a conventional or intensified schedule.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.